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DOK1 (phospho Y398), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Description
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq
Spécification
Spécification
| Antigène | DOK1 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic phosphopeptide of DOK1. |
| Dilution | Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formule | In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Expression | DOK1 |
| Numéro d’ordre du gène | Q99704 |
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For Research Use Only
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