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RAD23B Monoclonal Antibody (OTI8E5), TrueMAB™, OriGene
Description
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Spécification
Spécification
| Antigène | RAD23B |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | OTI8E5 |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Expression | RAD23B |
| Numéro d’ordre du gène | P54727 |
| Alias de gène | HHR23B, HR23B, P58 |
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Nom du produit
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