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Invitrogen™ RCC1 Polyclonal Antibody

Description
Recommended positive controls: 293T, A431, Raji. Predicted reactivity: Mouse (93%), Rat (93%), Xenopus laevis (81%), Dog (96%), Rabbit (96%), Chimpanzee (100%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Spécification
Spécification
| Antigène | RCC1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Formule | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| Expression | RCC1 |
| Numéro d’ordre du gène | P18754 |
| Alias de gène | 4931417M11Rik; AI326872; Cell cycle regulatory protein; chc1; chc1-a; chromosome condensation 1; chromosome condensation protein 1; fj77f08; guanine nucleotide-releasing protein; RanGEF; RCC1; rcc1.L; rcc1-a; rcc1-b; RCC1-I; Regulator of chromosome condensation; regulator of chromosome condensation 1; regulator of chromosome condensation 1 L homeolog; SNHG3-RCC1; SNHG3-RCC1 readthrough; wu:fj77f08; XELAEV_18012073mg; xrcc1; zgc:65796; zgc:77114 |
| Symboles de gène(s) | RCC1 |
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Nom du produit
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