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Invitrogen™ SENP5 Polyclonal Antibody

Description
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (97%), Xenopus laevis (82%), Rhesus Monkey (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the 'GG' region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
Spécification
Spécification
| Antigène | SENP5 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Expression | SENP5 |
| Numéro d’ordre du gène | Q96HI0 |
| Alias de gène | 6230429P13Rik; A730063F07Rik; AI851888; BB189556; DKFZp564O1016; FKSG45; FLJ42398; MGC27076; Senp5; sentrin/SUMO-specific protease SENP5; Sentrin-specific protease 5; SMT3IP3; SUMO/sentrin specific peptidase 5; SUMO/sentrin specific protease 5; SUMO/Smt3-specific isopeptidase 3; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; Sumo1/sentrin/SMT3 specific peptidase 5 |
| Symboles de gène(s) | SENP5 |
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Nom du produit
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