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Invitrogen™ SPDL1 Polyclonal Antibody
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Product Code. 16653535
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100 μL
Unit Size:
100µL
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16653535 100 μL 100µL
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Product Code. 16653535 Supplier Invitrogen™ Supplier No. PA599285

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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CCDC99.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
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Specifications

Antigène SPDL1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Expression SPDL1
Numéro d’ordre du gène Q923A2, Q96EA4
Alias de gène 1700018I02Rik; 2600001J17Rik; 2810049B11Rik; AA409762; arsenite-related gene 1 protein; Ccdc99; coiled-coil domain containing 99; coiled-coil domain-containing protein 99; coiled-coil domain-containing protein 99 {ECO:0000255; HAMAP-Rule:MF_03041}; hSpindly; protein Spindly; RGD1306908; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; SPDL1; Spindle apparatus coiled-coil domain-containing protein 1; spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255; spindle apparatus coiled-coil protein 1; spindly homolog
Symboles de gène(s) SPDL1
Espèces hôtes Rabbit
Immunogène A synthesized peptide derived from human SPDL1(Accession Q96EA4), corresponding to amino acid residues S576-Q605.
Méthode de purification Affinity Chromatography
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 54908, 70385
Espèces cibles Human, Mouse
Contenu et stockage -20°C
Type de produit Antibody
Forme Liquid
Isotype IgG
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