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  6. Invitrogen™ T-bet Recombinant Rabbit Monoclonal Antibody (8V7M8)

Invitrogen™ T-bet Recombinant Rabbit Monoclonal Antibody (8V7M8)

Code produit 30283161
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Quantité:
20 μL
100 μL
Conditionnement:
100µL
20µL
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Code produit Quantité Conditionnement
30283161 100 μL 100µL
30284407 20 μL 20µL
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Product Code. 30283161 Supplier Invitrogen™ Supplier No. MA558098
  • ONLINE EXCLUSIVE PRICE
    457.00€
    425.01€ / 100µL
    Économisez 31.99€
    7% de réduction
 Article restreint
Expédition estimée: 01-12-2026
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: KGFRENFESM YTSVDTSIPS PPGPNCQFLG GDHYSPLLPN QYPVPSRFYP DLPGQAKDVV PQAYWLGAPR DHSYEAEFRA VSMKPAFLPS APGPTMSYYR GQEVLAPGAG WPVAPQYPPK MGPASWFRPM RTLPMEPGPG GSEGRGPEDQ GPPLVWTEIA PIRPESSDSG LGEGDSKRRR VSPYPSSGDS SSPAGAPSPF DKEAEGQFYN YFPN.

T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
TRUSTED_SUSTAINABILITY

Specifications

Antigène T-bet
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 8V7M8
Concentration 1.08 mg/mL
Conjugué Unconjugated
Formule PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
Expression Tbx21
Numéro d’ordre du gène Q9UL17
Alias de gène HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Symboles de gène(s) Tbx21
Espèces hôtes Rabbit
Immunogène Recombinant fusion protein containing a sequence corresponding to amino acids 322-535 of human T-bet/Tbx21 (NP_037483.1).
Méthode de purification Protein A
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 30009
Espèces cibles Human
Contenu et stockage -20°C, Avoid Freeze/Thaw Cycles
Type de produit Antibody
Forme Liquid
Isotype IgG
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