missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Anticorps
  4. Anticorps primaires
  5. Tous les anticorps primaires
  6. Invitrogen™ T-bet Recombinant Rabbit Monoclonal Antibody (8V7M8)

Invitrogen™ T-bet Recombinant Rabbit Monoclonal Antibody (8V7M8)
GREENER_CHOICE

Code produit. 30283161
Change view
Click to view available options
Quantité:
20 μL
100 μL
Unit Size:
100µL
20µL
Product Code. Quantité unitSize
30283161 100 μL 100µL
30284407 20 μL 20µL
2 options
This item is not returnable. View return policy

Product Code. 30283161

Brand: Invitrogen™ MA558098

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!

This item is not returnable. View return policy

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: KGFRENFESM YTSVDTSIPS PPGPNCQFLG GDHYSPLLPN QYPVPSRFYP DLPGQAKDVV PQAYWLGAPR DHSYEAEFRA VSMKPAFLPS APGPTMSYYR GQEVLAPGAG WPVAPQYPPK MGPASWFRPM RTLPMEPGPG GSEGRGPEDQ GPPLVWTEIA PIRPESSDSG LGEGDSKRRR VSPYPSSGDS SSPAGAPSPF DKEAEGQFYN YFPN.

T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
TRUSTED_SUSTAINABILITY

Specifications

Antigène T-bet
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 8V7M8
Concentration 1.08 mg/mL
Conjugué Unconjugated
Formule PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
Expression Tbx21
Numéro d’ordre du gène Q9UL17
Alias de gène HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Symboles de gène(s) Tbx21
Espèces hôtes Rabbit
Immunogène Recombinant fusion protein containing a sequence corresponding to amino acids 322-535 of human T-bet/Tbx21 (NP_037483.1).
Méthode de purification Protein A
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 30009
Espèces cibles Human
Contenu et stockage -20°C, Avoid Freeze/Thaw Cycles
Type de produit Antibody
Forme Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.