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Invitrogen™ Thyroglobulin Monoclonal Antibody (TG8.1), Invitrogen™
Description
MA1-10595 detects Thyroglobulin, specifically both T3 and T4, from human samples. MA1-10595 has been successfully used in ELISA applications. The MA1-10595 immunogen is purified human Thyroglobulin.
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
Spécification
Spécification
| Antigène | Thyroglobulin |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | TG8.1 |
| Concentration | 1.2 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with no preservative; pH 7.4 |
| Expression | TG |
| Numéro d’ordre du gène | P01266 |
| Alias de gène | AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor |
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Nom du produit
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