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Invitrogen™ TRIP10 Polyclonal Antibody

Description
Immunogen sequence: LQRFNRDQAHF YFSQMPQIFD KLQDMDERRA TRLGAGYGLL SEAELEVVPI IA Highest antigen sequence identity to the following orthologs - mouse 96%, rat 89%.
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Spécification
Spécification
| Antigène | TRIP10 |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Expression | Trip10 |
| Numéro d’ordre du gène | Q15642 |
| Alias de gène | AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10 |
| Symboles de gène(s) | Trip10 |
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Nom du produit
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