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Invitrogen™ UNC5CL Polyclonal Antibody

Description
Recommended positive controls: Raji. Predicted reactivity: Human (99%), Mouse (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
UNC5CL is a membrane protein belonging to theUNC-5 family with a death domain and a ZU5 domain and is known to interact with p65/RELA and NFKB1. UNC5CL is known to interact with subunit p105 of NF-kappaB and transactivator p65 and is thus involved in inhibition of NF-kappaB activation and NF-kappaB-dependent transcription by inhibiting the binding of NF-kappaB to its target sequence (providing an alternative regulatory mechanism for NF-kappaB-mediated transcription). This regulatory protein sensitizes cells to apoptosis induced by TNF and TRAIL.
Spécification
Spécification
| Antigène | UNC5CL |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Expression | UNC5CL |
| Numéro d’ordre du gène | Q8IV45 |
| Alias de gène | 2510009H09Rik; BB155270; MGC34763; MUXA; OTTHUMP00000016362; protein unc-5 homolog C-like; unc-5 family C-terminal like; unc-5 homolog C (C. elegans)-like; UNC5CL; UNC5C-like protein; zu-5; ZU5 and death domain containing; ZU5 and death domain-containing inhibitor of NF-kB; ZU5 and death domain-containing protein; ZUD |
| Symboles de gène(s) | UNC5CL |
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Nom du produit
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