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Invitrogen™ Vitronectin Monoclonal Antibody (A18)

Code produit 11554162
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400 μL
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11554162 400 μL
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Code produit 11554162 Fournisseur Invitrogen™ Code fournisseur CSI0041802

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Description

Mouse Monoclonal Antibody

CSI 004-18-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 004-18-02 cross-reacts with rabbit and horse vitronectin, no reactivity with human or sheep. CSI 004-18-02 has been successfully used in ELISA and Immunohistochemistry techniques. CSI 004-18-02 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues. The antibody inhibits integrin-mediated cell adhesion to bovine vitronectin. It can be used to probe vitronectin conformation. CSI 004-18-02 reacts weakly in ELISA with vitronectin coated directly onto the microtiter plate. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
TRUSTED_SUSTAINABILITY

Spécification

Antigène Vitronectin
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone A18
Concentration 1.03 mg/mL
Conjugué Unconjugated
Formule PBS with 15mM sodium azide; pH 7.4
Expression VTN
Numéro d’ordre du gène P22458
Alias de gène Aa1018; AI256434; complement S-protein; epibolin; extracellular matrix protein; glycoprotein 66; serum spreading factor; serum-spreading factor; somatomedin B; Somatomedin-B; S-protein; V75; Vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin V10 subunit; Vitronectin V65 subunit; VN; VNT; VTN
Symboles de gène(s) VTN
Espèces hôtes Mouse
Immunogène Lysed bovine corneal endothelial cells and extracellular matrix.
Méthode de purification Protein A
Quantité 400 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 100009128, 100059034, 507525
Espèces cibles Rabbit, Bovine, Horse
Contenu et stockage 4°C, store in dark
Type de produit Antibody
Forme Liquid
Isotype IgG1 κ
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