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CAST, Mouse, Clone: 2C5, Abnova™
Mouse monoclonal antibody raised against a partial recombinant CAST.
Brand: Abnova H00000831-M03.100ug
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Description
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length natures of only some have been determined. [provided by RefSeq
Sequence: QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQSpecifications
| CAST | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_001750 | |
| CAST | |
| CAST (NP_001741.3, 582 a.a. ∼ 669 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 κ |
| ELISA, Immunofluorescence, Western Blot | |
| 2C5 | |
| Mouse monoclonal antibody raised against a partial recombinant CAST. | |
| CAST | |
| BS-17/MGC9402 | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 831 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |
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