Learn More
CLA-1 Mouse anti-Human, Unlabeled, Clone: 25, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 610883
Description
CLA-1 (CD36 and LIMPII Analogous-1) is member of a novel gene family that includes CD36, LIMPII, and SR-BI. CD36 is a cell surface glycoprotein that binds to collagen type I and thrombospondin. LIMPII (lysosomal integral membrane protein II), as its name suggests, is expressed on the membrane of lysosomes. SR-BI (scavenger receptor type B class I) is involved in the selective uptake of cholesterol esters. These proteins include two membrane-anchoring regions, two short cytoplasmic tails, and a large extracellular/luminal domain. CLA-1 mRNA is detected in a wide range of tissues including adrenal glands, liver, and testis. Its expression and similarity with other family members suggest it may play a role in HDL metabolism. However, identification of the CLA-1 receptor on monocytes indicates additional CLA-1 functions in leukocytes.
Immunofluorescence, Western Blotting
Spécification
| CLA-1 | |
| Monoclonal | |
| 250μg/mL | |
| CD36 and LIMPII Analogous-1 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at -20°C. |
| Western Blot | |
| 25 | |
| Unconjugated | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Human CLA-1 aa. 104-294 | |
| 150 μg | |
| Cell Biology | |
| Human | |
| IgG1 |
Veuillez fournir vos retours sur le contenu du produit en remplissant le formulaire ci-dessous.
For Research Use Only.