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IGF1R alpha Monoclonal Antibody (24-57), Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen MA513812

Code nomenclature Nacres: NA.41

Informations supplémentaires : Poids : 0.01000kg

Code produit. 11364923

  • 451.00€ / 500µL
Expédition estimée: 04-06-2024
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Description

Description

MA5-13812 targets IGF-1 Receptor alpha in IA and IP applications and shows reactivity with Human and Rabbit samples. The MA5-13812 immunogen is iGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of malignant cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
Spécification

Spécification

IGF1R alpha
Monoclonal
0.2 mg/mL
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P08069
Igf1r
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
500 μL
Primary
Human, Rabbit
Antibody
IgG1 κ
Immunoprecipitation, Inhibition Assays
24-57
Unconjugated
Igf1r
A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Mouse
Protein G
RUO
100144342, 3480
4° C
Liquid
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