missing translation for 'onlineSavingsMsg'
Learn More
Learn More
INF-g Mouse anti-Human, PE-Cy7, Clone: B27, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 560924
Les retours ne sont pas autorisés pour ce produit.
Afficher la politique du retour.
Description
The B27 monoclonal antibody specifically binds to human interferon-γ (IFN-γ). IFN-γ is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ+ T cells. IFN-γexerts its biological effects through specific binding to the high-affinity IFN-γ Receptor Complex comprised of IFN-γβ subunits. In addition to its antiviral effects, IFN-γupregulates a number of lymphoid cell functions including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. In addition, IFN-γcan exert strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. These influences can involve IFN-γ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γis a 14-18 kDa glycoprotein containing 143 amino acid residues. B27 is a neutralizing antibody. The use of B27 antibody for epitope mapping of human IFN-γ has been described. The B27 antibody has been reported not to bind to denatured IFN-γ.
Spécification
| INF-g | |
| Monoclonal | |
| PE-Cyanine7 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| B27 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human IFN-γ Recombinant Protein | |
| 25 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Correction du contenu d'un produit
Veuillez fournir vos retours sur le contenu du produit en remplissant le formulaire ci-dessous.
Nom du produit
Vous avez repéré une opportunité d'amélioration ?Partager une correction de contenu