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Invitrogen™ TRIM21 Polyclonal Antibody
Goat Polyclonal Antibody
Marque: Invitrogen™ PA518147
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
Spécification
| TRIM21 | |
| Polyclonal | |
| Unconjugated | |
| TRIM21 | |
| 52 kDa ribonucleoprotein autoantigen Ro/SS-A; 52 kDa Ro protein; 52kD Ro/SSA autoantigen; E3 ubiquitin-protein ligase TRIM21; RING finger protein 81; RING-type E3 ubiquitin transferase TRIM21; RNF81; Ro(SS-A); Ro/SSA; RO52; Sicca syndrome antigen A; sjoegren syndrome type A antigen; Sjogren syndrome antigen A1; Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); SSA; SS-A; Ssa1; TRIM21; tripartite motif containing 21; tripartite motif protein 21; tripartite motif-containing 21; tripartite motif-containing protein 21 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 6737 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P19474 | |
| TRIM21 | |
| Synthetic peptide sequence (CPLNIGSQGSTDY) corresponding to the C-terminus amino acids of TRIM21 (aa 463-475). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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