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SSEA-4 Mouse, PerCP-Cy5.5, Clone: MC813-70, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 561565
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Description
The MC813-70 monoclonal antibody reacts with Stage-Specific Embryonic Antigen-4 (SSEA-4), a carbohydrate epitope on the major ganglioside, but not the neutral glycolipid, of human teratocarcinoma cells. As its name implies, the expression of SSEA-4 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-4 is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (ICM), embryonic stem (ES) cells, and the K562 erythromyeloid leukeumia cell line. As human stem cells undergo differentiation, SSEA-4 expression is lost. In the mouse, SSEA-4 is found on oocytes and early cleavage-stage embryos, and primitive ectoderm, but not on EC, ICM, or ES cells. In some cases, SSEA-4 expression appears upon differentiation of mouse EC or ES cells.
Spécification
| SSEA-4 | |
| Monoclonal | |
| PerCP-Cyanine5.5 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human Teratocarcinoma Cell Line | |
| 50 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| MC813-70 | |
| Stage-Specific Embryonic Antigen-4 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human, Mouse | |
| IgG3 κ |
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