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β-Tubulin, Class III Mouse, Alexa Fluor 488, Clone: TUJ1, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 560381
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Description
Microtubules are formed by the self assembly of tubulin and are one of the major components of the eukaryotic cytoskeleton. The two main tubulin isoforms, α - and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.
Spécification
| β-Tubulin, Class III | |
| Monoclonal | |
| Alexa Fluor 488 | |
| Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. | |
| Rat brain microtubules | |
| 50 Tests | |
| Cell Biology | |
| Human, Rat | |
| IgG2a |
| Flow Cytometry | |
| TUJ1 | |
| tubulin, beta 3; MC1R; TUBB3; TUBB4; tubulin, beta-4 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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