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BCR Rabbit anti-Human, Non-human primate, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 22585-1-AP-150UL

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Code produit. 16801995

  • 399.00€ / 150µL

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Description

Description

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Spécification

Spécification

BCR
Polyclonal
Unconjugated
BCR
ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL
Rabbit
Antigen Affinity Chromatography
RUO
613
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
0.45 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P11274
BCR
BCR Fusion Protein Ag18281
150 μL
Primary
Human, Non-human Primate
Antibody
IgG
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