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BCR Rabbit anti-Human, Non-human primate, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 22585-1-AP-150UL
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Description
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.Spécification
| BCR | |
| Polyclonal | |
| Unconjugated | |
| BCR | |
| ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 613 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| 0.45 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P11274 | |
| BCR | |
| BCR Fusion Protein Ag18281 | |
| 150 μL | |
| Primary | |
| Human, Non-human Primate | |
| Antibody | |
| IgG |