Invitrogen™ Blood Group A1, A2, A3 Antigen Monoclonal Antibody (Z2B-1)

Description

MA1-7665 detects A1, A2, A3 human blood protein from human samples. MA1-7665 has been successfully used in agglutination applications. The MA1-7665 immunogen is A1, A2, A3 human blood protein.

Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.