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CD105 (Endoglin) Mouse, anti-Human, APC, Clone: 43A3, STEMCELL Technologies
Mouse Monoclonal Antibody
Marque: Stemcell Technologies 60039AZ
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Description
- The 43A3 antibody reacts with CD105 (endoglin), an ∼180 kDa cell surface glycoprotein which is a disulfide-bonded homodimer of ∼90 kDa type I transmembrane subunits
- CD105 is a component of the TGF-β receptor complex and is expressed by vascular endothelial smooth muscle cells, syncytiotrophoblasts of placenta and activated macrophages, and at relatively low levels by stromal fibroblasts
- Its expression is also observed in some types of tumors, and levels are up-regulated on the endothelium during angiogenesis
- CD105 has important roles in angiogenesis, cardiovascular development, and vascular remodeling, and the protein serves a regulatory role in cytoskeletal reorganization by modulating the sites of focal adhesion and cellular migration
- This antibody clone has been verified for labeling human mesenchymal cells grown in MesenCult™ Proliferation Kit (Human; Catalog #05411) and MesenCult™-XF Medium (Catalog #05420)
Spécification
| CD105 (Endoglin) | |
| Monoclonal | |
| APC | |
| 100 Tests | |
| Human, Mouse | |
| Hematopoietic Stem and Progenitor Cells, Mesenchymal Stem and Progenitor Cells |
| Immunoprecipitation, Western Blot, Flow Cytometry | |
| 43A3 | |
| Mouse | |
| Primary | |
| IgG1 κ |
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