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CD144 (VE-cadherin) Monoclonal Antibody (eBioBV13 (BV13)), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
2985.00€ - 14910.00€
Spécification
| Antigène | CD144 (VE-cadherin) |
|---|---|
| Clone | eBioBV13 (BV13) |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
Beskrivning
The BV13 MAb reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.
CD144 (VE-cadherin) Monoclonal antibody specifically detects CD144 (VE-cadherin) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western BlotSpecifikationer
| CD144 (VE-cadherin) | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; CD144; cd144 antigen; Cdh5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |
| eBioBV13 (BV13) | |
| Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot | |
| Functional Grade | |
| Rat | |
| Mouse | |
| P55284 | |
| 12562 | |
| Primary | |
| 4° C | |
| CDH5 |
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