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  6. CD282 (TLR2) Monoclonal Antibody (TL2.1), Functional Grade, eBioscience™, Invitrogen™
  7. 17171622

CD282 (TLR2) Monoclonal Antibody (TL2.1), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 16-9922-050

Code nomenclature Nacres: NA.46

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Product Code. 17171622

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Description

Description

The TL2.1 MAb reacts with human Toll-like receptor 2 (TLR2). To date, at least ten members of the Toll family have been identified in human. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed by peripheral blood monocytes and is responsible for distinguishing different pathogens. TL2.1, a blocking antibody, has been used to study the role of TLR-2 as a pattern recognition receptor in microbial lipoprotein/lipopeptide induced cytokine production from human peripheral blood mononuclear cells. TL2.1 has been reported to immunoprecipitate human TLR2 (∽90 kDa) from PBMC and HMEC.

CD282 (TLR2) Monoclonal antibody specifically detects CD282 (TLR2) in Human samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD282 (TLR2)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
O60603
Mouse
50 mg
Primary
Human
Antibody
IgG2a κ
Flow Cytometry, Functional Assay, Neutralization
TL2.1
Functional Grade
Tlr2
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; Toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Affinity chromatography
RUO
7097
4° C
Liquid
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