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CD283 (TLR3) Monoclonal Antibody (TLR3.7), Functional Grade, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Marque: Affymetrix eBioscience 16-9039-050
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Description
The TLR3.7 MAb reacts with human Toll-like receptor 3 (TLR3). To date, at least twelve members of the Toll-like receptor family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immune response, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial activity. TLR3 recognizes double-stranded (ds)RNA, induces the activation of NF-kappaB through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). TLR3.7 suppressed poly(I):poly(C)-mediated IFN-beta production by human fibroblasts naturally expressing TLR3 on their surface.
CD283 (TLR3) Monoclonal antibody specifically detects CD283 (TLR3) in Human samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
Spécification
| CD283 (TLR3) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| O15455 | |
| Mouse | |
| 50 mg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry, Functional Assay, Neutralization | |
| TLR3.7 | |
| Functional Grade | |
| TLR3 | |
| AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1 | |
| Affinity chromatography | |
| RUO | |
| 7098 | |
| 4° C | |
| Liquid |
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