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CD31 Monoclonal Antibody (390), Pacific Blue™, Invitrogen™

Rat Monoclonal Antibody

Marque:  Invitrogen RM5228

Code nomenclature Nacres: NA.41

Informations supplémentaires : Poids : 0.00100kg

Code produit. 10013384

  • 374.00€ / 1 pièce
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Description

Description

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Spécification

Spécification

CD31
Monoclonal
0.1 mg/mL
PBS with 0.1% sodium azide
Q08481
Pecam1
Mouse 32D leukocyte cell line.
1 mL
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry
390
Pacific Blue
Pecam1
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Rat
Affinity chromatography
RUO
18613
4° C
Liquid
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