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Invitrogen™ CD365 (TIM1) Monoclonal Antibody (1D12-TIM1), PE-Cyanine7, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Marque: Invitrogen™ 25-3659-41
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Description
Mouse Monoclonal Antibody
CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.
Spécification
| CD365 (TIM1) | |
| Monoclonal | |
| 5 μL/Test | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| Q96D42 | |
| Havcr1 | |
| IgV domain of human CD365. | |
| 25 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry | |
| 1D12-TIM1 | |
| PE-Cyanine7 | |
| Havcr1 | |
| AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1 | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 26762 | |
| 4°C, store in dark, DO NOT FREEZE! | |
| Liquid |
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