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CD62P Rat anti-Mouse, FITC, Clone: RB40.34, BD
Rat Monoclonal Antibody
Marque: BD Biosciences 553744
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Description
The RB40.34 monoclonal antibody specifically binds to mouse P-selectin (CD62P), a 140 kDa protein which is expressed on activated platelets, activated endothelial cells, and megakaryocytes. P-selectin mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells, mediates leukocyte rolling, and is involved in the migration of leukocytes into inflamed tissues. CD24 and CD162 (PSGL-1) are ligands of CD62P. mAb RB40.34 can block mouse P-selectin binding to its ligands in vitro and in vivo.
Spécification
| CD62P | |
| Monoclonal | |
| 0.5mg/mL | |
| P-selectin; Selp; LECAM3; LYAM3; PADGEM; GMP-140; Grmp | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| RB40.34 | |
| FITC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| P-selectin-IgG1 Fusion | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG1 λ |
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Nom du produit
For Research Use Only.
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