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  6. CD85j (ILT2) Monoclonal Antibody (HP-F1), APC-eFluor™ 780, eBioscience™, Invitrogen™
  7. 16676364

CD85j (ILT2) Monoclonal Antibody (HP-F1), APC-eFluor™ 780, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 47-5129-41

Code nomenclature Nacres: NA.46

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Code produit. 16676364

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Description

Description

The MAb HP-F1 recognizes CD85j, also known as ILT2, LILRB1, and LIR1. CD85j is a member of the ILT (immunoglobulin-like transcript)/LIR (leukocyte Ig-like receptor)/MIR (monocyte Ig-like receptor) family. CD85j is a single transmembrane glycoprotein with a long cytoplasmic domain containing 4 ITIMs which signal through interactions with SHP-1. Expression is found on myeloid cells (monocytes and dendritic cells) and some lymphoid cells including, subsets of NK, T and B cells. Expression has been correlated with leukemias such as ALL and CLL. Expression on CD8+ cells correlates with effector cell function and plays an important role in viral infections, including HIV, Ebstein Barr and CMV. The ligands for CD85j are MHC Class I molecules such as HLA-G, A, F, B27, E and F. The MAb HP-F1 has been shown to reduce the amount of CD16- dependent cytolytic activity of functional NK cells.

CD85j (ILT2) Monoclonal antibody specifically detects CD85j (ILT2) in Human samples. It is validated for Flow Cytometry
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD85j (ILT2)
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q8NHL6
Mouse
25 Tests
Primary
Human
Antibody
IgG1 κ
Flow Cytometry
HP-F1
APC-eFluor 780
LILRB1
CD85 antigen-like family member J; CD85j; Ig-like transcript 2; ILT2; ILT-2; Immunoglobulin-like transcript 2; leucocyte Ig-like receptor B1; leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor subfamily B member 3-like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR1; LIR-1; LOC100912456; MIR7; MIR-7; Monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B
Affinity chromatography
RUO
10859
4° C, store in dark, DO NOT FREEZE!
Liquid
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