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CD85j (ILT2) Monoclonal Antibody (HP-F1), APC-eFluor™ 780, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Marque: Affymetrix eBioscience 47-5129-41
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Description
The MAb HP-F1 recognizes CD85j, also known as ILT2, LILRB1, and LIR1. CD85j is a member of the ILT (immunoglobulin-like transcript)/LIR (leukocyte Ig-like receptor)/MIR (monocyte Ig-like receptor) family. CD85j is a single transmembrane glycoprotein with a long cytoplasmic domain containing 4 ITIMs which signal through interactions with SHP-1. Expression is found on myeloid cells (monocytes and dendritic cells) and some lymphoid cells including, subsets of NK, T and B cells. Expression has been correlated with leukemias such as ALL and CLL. Expression on CD8+ cells correlates with effector cell function and plays an important role in viral infections, including HIV, Ebstein Barr and CMV. The ligands for CD85j are MHC Class I molecules such as HLA-G, A, F, B27, E and F. The MAb HP-F1 has been shown to reduce the amount of CD16- dependent cytolytic activity of functional NK cells.
CD85j (ILT2) Monoclonal antibody specifically detects CD85j (ILT2) in Human samples. It is validated for Flow Cytometry
Spécification
| CD85j (ILT2) | |
| Monoclonal | |
| 5 μL/Test | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
| Q8NHL6 | |
| Mouse | |
| 25 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry | |
| HP-F1 | |
| APC-eFluor 780 | |
| LILRB1 | |
| CD85 antigen-like family member J; CD85j; Ig-like transcript 2; ILT2; ILT-2; Immunoglobulin-like transcript 2; leucocyte Ig-like receptor B1; leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor subfamily B member 3-like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR1; LIR-1; LOC100912456; MIR7; MIR-7; Monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B | |
| Affinity chromatography | |
| RUO | |
| 10859 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
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