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Description
Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates. This antibody is specific for the C-terminal region of the claudin-1 protein. On western blots, it identifies the target band at ~22 kDa.
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
Spécification
| Claudin 1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| O88551, O95832, P56745 | |
| CLDN1 | |
| Synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins. | |
| 100 μg | |
| Primary | |
| Canine, Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 2H10D10 | |
| Unconjugated | |
| CLDN1 | |
| AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944 | |
| Mouse | |
| Protein A | |
| RUO | |
| 12737, 608207, 65129, 9076 | |
| Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C | |
| Liquid |
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