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Fibrinogen Monoclonal Antibody (UC45), Invitrogen™
Mouse Monoclonal Antibody
Marque: Invitrogen MA126074
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Description
MA1-26074 detects alpha Fibrin from human samples. MA1-26074 reacts very strongly with the alpha chain of human fibrinogen. MA1-26074 has been successfully used in radioimmune assay and immunocytochemistry procedures. The MA1-26074 immunogen is human acute monoblastic leukemia cells.
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
Spécification
| Fibrinogen | |
| Monoclonal | |
| 1 mg/mL | |
| FGA | |
| FGA | |
| Human acute monoblastic leukemia cells. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgM |
| Immunocytochemistry, Immunofluorescence, Radioimmune Assays (RIA) | |
| UC45 | |
| Unconjugated | |
| P02671 | |
| Mouse | |
| Antigen affinity chromatography | |
| RUO | |
| 2243 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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