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Granzyme K Monoclonal Antibody (GM24C3), Invitrogen™
Mouse Monoclonal Antibody
Marque: Invitrogen MA117753
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Description
This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells.
Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
Spécification
| Granzyme K | |
| Monoclonal | |
| Unconjugated | |
| GZMK | |
| Fragmentin-3; granzyme 3; granzyme K; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); granzyme-3; GrK; GZMK; NK-Tryp-2; NK-tryptase-2; RNK-Tryp-2; TRYP2; tryptase II | |
| Mouse | |
| Protein G | |
| RUO | |
| 3003 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Flow Cytometry | |
| GM24C3 | |
| PBS with no preservative; pH 7.2 | |
| P49863 | |
| GZMK | |
| cDNA encoding human Granzyme K | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
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