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![H-2D[d] Mouse anti-Mouse, FITC, Clone: 34-2-12, BD 50μg; FITC:Anticorps,](https://assets.fishersci.com/TFS-Assets/CCG/product-images/F873679.jpg-650.jpg)
H-2D[d] Mouse anti-Mouse, FITC, Clone: 34-2-12, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 562001
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Description
The 34-2-12 antibody (also known as 34-2-12S) recognizes the α3 domain of the H-2D[d]. The binding of the antibody to its epitope is independent of the α1 and α2 domains and β2 microglobulin. It cross-reacts with cells of the C3H.LG/Ckc strain. Reactivity with other haplotypes (eg, b, f, k, p, q, r, s) has not been observed. Soluble mAb 34-2-12 blocks binding of the Ly-49A-expressing T lymphoma EL4 to immobilized H-2D[d]. However, further studies utilizing this mAb indicate that the α3 domain is not involved in the interaction between Ly-49A, or Ly-49G2, and H-2D[d].
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Spécification
| H-2D[d] | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| (C57BL/6 x DBA/2)F1 mouse splenocytes | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 34-2-12 | |
| FITC | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2a κ |
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Nom du produit
For Research Use Only.
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