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HLA-B7 Monoclonal Antibody (BB7.1), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 17-5917-42

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16370714

  • 348.00€ / 100 pièces
Expédition estimée: 29-05-2024
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Description

Description

Description: This BB7.1 monoclonal antibody recognizes the human major histocompatibility complex MHC class I molecule HLA-B7, which is a member of the HLA-B family. MHC class I exists as a heterodimer composed of a specific alpha chain associated with a beta 2-microglobulin. MHC class I molecules are expressed on all nucleated cells. Applications Reported: This BB7.1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This BB7.1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser

HLA-B7 is one of the polymorphic proteins of human MHC Class I found on all nucleated cells. This surface protein is a heterodimer consisting of the specific transmembrane HLA-B chain paired with Beta-2 microglobulin. Classical MHC Class I molecules play a central role in adaptive immunity by presenting to T cells antigenic peptides derived either from the cell itself (classical presentation) or extracellular antigens (cross-presentation). The ligands of MHC class I include T cell receptor (TCR) and a costimulatory molecule CD8. Hundreds of HLA-B alleles have been described. Typing for these polymorphisms is routinely done for transplantation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Spécification

Spécification

HLA-B7
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
P01889
HLA-B
Papain solubilized HLA-B7
100 Tests
Primary
Human
Antibody
IgG1 κ
Flow Cytometry
BB7.1
APC
HLA-B
A29 protein, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, CDABP0067, class I MHC, HLA-B antigen, DAQB-90C11.16, epididymis secretory protein Li 83, FLJ26655, HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, hla b7, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha
Mouse
Affinity chromatography
RUO
3106
4° C, store in dark, DO NOT FREEZE!
Liquid
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