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ACROBiosystems HRSV (A) Glycoprotein G Protein, His Tag

Marque:  ACROBiosystems RSG-V5221-50UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15877627

  • 353.08€ / 50µg
Date d’expédition estimée: 28-12-2021

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Description

Description

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. Human respiratory syncytial virus A (strain Long) major surface glycoprotein G (RSV-G), a member of the pneumoviruses glycoprotein G family, is also known as attachment glycoprotein G and membrane-bound glycoprotein (mG), which contains a linear heparin binding domain essential for virus attachment to the host. Concretely speaking, RSV-G can attache the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Furthermore, RSV-G can also interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, RSV-G lacks both neuraminidase and hemagglutinating activities.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 46-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

Less than 1.0 EU / µg by the LAL method.
Viral Proteins
Powder
>90% as determined by SDS-PAGE
HRSV (A) Glycoprotein G, His Tag (RSG-V5221) is expressed from human 293 cells (HEK293). It contains AA His 67 - Arg 297 (Accession # P20895).
-20°C
Glycoprotein G / G
His Tag
HEK293
HRSV
27.0 kDa
50 µg
His 67 - Arg 297
Glycoprotein G,G,mG,Attachment glycoprotein G,Membrane-bound glycoprotein
Unconjugated
PBS, pH7.4
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FDS
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