Human Serum Albumin Monoclonal Antibody (12D12), Invitrogen™

Description

MIH3005 targets Human Serum Albumin in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MIH3005 immunogen is human Serum Albumin. MIH3005 detects Human Serum Albumin which has a predicted molecular weight of approximately 67 kDa. MIH3005 was formerly sold as a Seradyn product.

Albumin is a soluble, monomeric protein with a molecular weight of approximately 65-67 kDa that comprises about one-half of the blood serum protein. Human serum albumin (HAS) is the most abundant protein in human blood plasma, and has a serum half-life of approximately 20 days. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular, unglycosylated serum protein synthesized in the liver as pre-pro-albumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough `produce the secreted albumin. Serum albumin has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. The main function of albumin is the regulation of the colloidal osmotic pressure of blood.