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Invitrogen™ IL1R2 Monoclonal Antibody (34141)
Mouse Monoclonal Antibody
Marque: Invitrogen™ MA523820
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Description
When used in combination with the biotinylated human IL-1 RII affinity purified polyclonal detection antibody in sandwich ELISAs, no significant cross-reactivity or interference was observed with recombinant human (rh) IL-1ra, rhIL-1 RI, recombinant mouse IL-1ra, or recombinant rat IL-1ra. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
Spécification
| IL1R2 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P27930 | |
| Il1r2 | |
| Sf 21-derived recombinant human IL-1 RII Phe14-Glu343 (Ser56Gly and Glu297Gly). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Neutralization, Western Blot | |
| 34141 | |
| Unconjugated | |
| Il1r2 | |
| antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 receptor beta chain; IL-1 type II receptor; Il1r2; Il-1r2; IL-1R-2; Il1r-2; IL1R2c; IL1RB; IL-1R-beta; IL-1RT2; IL-1RT-2; ILR2; interleukin 1 receptor type 2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type 2, membrane form; Interleukin-1 receptor type 2, soluble form; Interleukin-1 receptor type II; mIL-1R2; sIL-1R2; type II interleukin-1 receptor, beta | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 7850 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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