missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ IL23R Polyclonal Antibody
Goat Polyclonal Antibody
Marque: Invitrogen™ PA547184
Les retours ne sont pas autorisés pour ce produit.
Afficher la politique du retour.
Description
Approximately 15% cross-reactivity with recombinant human IL-23 R is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.
Spécification
| IL23R | |
| Polyclonal | |
| Unconjugated | |
| Il23r | |
| IBD17; IL 23R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 209590 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| Q8K4B4 | |
| Il23r | |
| Mouse myeloma cell line NS0-derived recombinant mouse IL-23 R Gly24-Asp372. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
Correction du contenu d'un produit
Veuillez fournir vos retours sur le contenu du produit en remplissant le formulaire ci-dessous.
Nom du produit
Vous avez repéré une opportunité d'amélioration ?Partager une correction de contenu