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Invitrogen™ LanthaScreen™ Tb-peIF2a (pSer52) Antibody

The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis.

Marque:  Invitrogen™ PV4816

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Code produit. 10023574

  • 20210.00€ / 1 pièce

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Description

Description

The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.

For use in combination with the GFP-EIF2alpha physiological protein substrate (Cat. No. PV4809) to evaluate inhibitors in medium to high throughput screening applications.

TRUSTED_SUSTAINABILITY
Spécification

Spécification

Serine/threonine kinase
0.47mg/mL
150kDa
RUO
Primary
Terbium-labeled peIF2a (pThr46) antibody in HEPES buffered saline. Store at -20°C.
340/490, 520 nm
Dry Ice
Hu
LanthaScreen™
Kinase Assay
Tb (Terbium)/Lanthanide Chelates
1 mg
Pharma and Biopharma
1 Each
Liquid
Human
End Point
Ser/Thr Kinases
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For Research Use Only. Not for use in diagnostic procedures.