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Mac-3 Rat anti-Mouse, FITC, Clone: M3/84, BD
Rat Monoclonal Antibody
1140.00€
Spécification
| Antigène | Mac-3 |
|---|---|
| Clone | M3/84 |
| Concentration | 0.5mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
15847148
|
BD Biosciences
553323 |
0.5 mg | |||||||
Description
The M3/84 monoclonal antibody specifically binds to CD107b which is also known as Mac-3, Lysosome-associated membrane protein 2 (LAMP-2/Lamp2/Lamp II), and Lysosomal membrane glycoprotein type B (LGP-B). CD107b is a single-pass type I transmembrane glycoprotein that constitutes a major integral membrane protein of lysosomes and may play a role in lysosomal function. CD107b is also expressed on the surface of mouse mononuclear phagocytes. Surface expression of the 92-110-kDa glycoprotein antigen increases during differentiation of monocytes to activated macrophages and may play a role in adhesion. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.
Spécification
| Mac-3 | |
| 0.5mg/mL | |
| Monoclonal | |
| Rat | |
| Mouse | |
| Mouse C57Bl/6 peritoneal exudate cells | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| M3/84 | |
| Flow Cytometry | |
| FITC | |
| RUO | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| IgG1 κ | |
| Affinity Purified |
For Research Use Only.
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