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MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
2985.00€ - 14910.00€
Spécification
| Antigène | MHC Class II (I-A/I-E) |
|---|---|
| Clone | M5/114.15.2 |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay, Neutralization |
| Classification | Monoclonal |
Description
The M5/114.15.2 MAb reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
MHC Class II (I-A/I-E) Monoclonal antibody specifically detects MHC Class II (I-A/I-E) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, NeutralizationSpécification
| MHC Class II (I-A/I-E) | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| Abeta; AI845868; cell surface glycoprotein; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ab; H2-Ab; H2-Ab1; H2Eb; H-2Eb; H2-Eb1; H2-iabeta; histocompatibility 2, class II antigen A, beta 1; histocompatibility 2, class II antigen E beta; Ia2; Ia-2; Ia4; Ia-4; IAb; I-Ab; I-Abeta; I-Ad; I-Aq; I-E beta MHC class II; I-Ed; I-Ek; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; MHC class 2; MHC class II antigen A beta; MHC class II H2-IA-beta-psi; MHC class II IE-b; MHC H2-IE-beta cell surface glycoprotein; response to metastatic cancers 1; Rmcs1 | |
| IgG2b κ | |
| Affinity chromatography | |
| Antibody |
| M5/114.15.2 | |
| Flow Cytometry, Functional Assay, Neutralization | |
| Functional Grade | |
| Rat | |
| Mouse | |
| P01921, P04230, P06342, P06343, P06344, P06345, P06346, P14483 | |
| 14961, 14969 | |
| Primary | |
| 4° C | |
| H2-Ab1 |
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