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MHC Class II I-Ad Mouse anti-Mouse, APC, Clone: AMS-32.1, eBioscience™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 17-5323-80

Code nomenclature Nacres: NA.41

Informations supplémentaires : Poids : 0.25000kg

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Code produit. 15330740

  • 74.25€ / 25µg

En stock, prêt à être expédié : 1

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Description

Description

MHC class II molecules are heterodimers of non-covalently associated alpha (31-34 kDa) and beta (26-29 kDa) chains. Major histocompatibility complex class II antigen presentation requires the participation of lysosomal proteases in two convergent processes. First, the antigens endocytosed by the antigen presenting cells must be broken down into antigenic peptides. Second, class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lymphocytes, which are usually T helper cells. CD4 interacts with non-polymorphic residues of MHC class II.
Spécification

Spécification

MHC Class II I-Ad
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P06342
H-2 class II histocompatibility antigen A beta chain, H2-AB1, H2-iabeta
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
AMS-32.1
APC
H2-Ab1
Liquid
H2-Ab1
IgG2b, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
14961
Vidéos
Documents

For Research Use Only.