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ACROBiosystems Mouse CLEC12A / MICL / CLL-1 Protein, His Tag

Marque:  ACROBiosystems CLA-M5244-1mg

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17266180

  • 2896.79€ / 1mg
Expédition estimée: 03-01-2023
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Description

Description

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.7 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

25.7 kDa
1 mg
Tyr 65 - Arg 267
CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
Unconjugated
PBS, pH7.4
HEK293
Bio-Markers & CD Antigens
>90% as determined by SDS-PAGE.
Mouse CLEC12A, His Tag (CLA-M5244) is expressed from human 293 cells (HEK293). It contains AA Tyr 65 - Arg 267 (Accession # Q504P2-1).
-20°C
CLEC12A
His Tag
Less than 1.0 EU / µg by the LAL method.
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