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OPA1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1B2D8, Proteintech
Mouse Monoclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | OPA1 |
---|---|
Clone | 1B2D8 |
Concentration | 1 mg/mL |
Applications | Western Blot |
Classification | Monoclonal |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16828595
|
Proteintech
66583-1-IG-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 14-05-2024 Connectez-vous pour voir le stock disponible |
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16818595
|
Proteintech
66583-1-IG-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 14-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
OPA1 is a dynamin-related GTPase that is critical for the maintece of mitochondrial morphology and mtDNA. The most commonly associated phenotype with OPA1 mutations is heterozygous optic atrophy, a heterozygous domit trait that causes reduced visual clarity and sometimes blindness. The disease usually begins in childhood and increases in severity throughout the life of affected individuals. Usually, this phenotype is attributed to the degeneration of optic nerve fibers. Interestingly, the same type of nerve degeneration seems to be partially causative of certain schizophrenia characteristics. OPA1 dysfunction also seems to be implicated in this case; mitochondrial networks associated with critical nerves seem to link schizophrenia and OPA1. The dysfunction is associated with issues with apoptosis and normal cellular metabolic regulation, all regulated through OPA1.Spécification
OPA1 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
KIAA0567, largeG, MGM1, NTG, OPA1, Optic atrophy protein 1 | |
Opa1 | |
IgG2b | |
Protein A | |
Antibody |
1B2D8 | |
Western Blot | |
Unconjugated | |
Mouse | |
Mouse, Porcine, Human, Rat | |
O60313, P58281, Q2TA68 | |
100522705, 171116, 4976, 74143 | |
OPA1 Fusion Protein Ag26868 | |
Primary | |
-20°C | |
OPA1 |