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Perlecan Monoclonal Antibody (A7L6), Invitrogen™

Rat Monoclonal Antibody

Marque:  Invitrogen MA514641

Code nomenclature Nacres: NA.46

Code produit. 11365113

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Description

Description

MA5-14641 targets Perlecan in IF, IHC (F), and IHC (P, F) applications and shows reactivity with Bovine, Human, mouse, and Porcine samples. The MA5-14641 immunogen is mouse EHS laminin preparation.

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
TRUSTED_SUSTAINABILITY
Spécification

Spécification

Perlecan
Monoclonal
0.2 mg/mL
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P98160, Q05793
HSPG2
Murine EHS laminin preparation
500 μL
Primary
Bovine, Human, Mouse, Pig
Antibody
IgG2a κ
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
A7L6
Unconjugated
HSPG2
AI852380; Basement membrane-specific heparan sulfate proteoglycan core protein; Endorepellin; endorepellin (domain V region); heparan sulfate proteoglycan 2; HSPG; Hspg2; LG3 peptide; LOC313641; Pcn; per; perlecan; perlecan (heparan sulfate proteoglycan 2); perlecan proteoglycan; PLC; PRCAN; RP11-132G19.2; SJA; SJS; SJS1
Rat
Protein G
RUO
100517288, 15530, 3339, 444872
4° C
Liquid
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