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PGRMC2 Mouse anti-Human, Mouse, Clone: 5F10D7, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60249-1-IG-20UL
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Description
PGRMC2 has a calculated molecular weight of 24 kDa. The band of about 28 kDa detected by this monoclonal antibody is unknown but may represent phosphorylated form of PGRMC2.
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.Specifications
| PGRMC2 | |
| Monoclonal | |
| 1.5 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O15173, Q80UU9 | |
| Pgrmc2 | |
| PGRMC2 Fusion Protein Ag20077 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Western Blot | |
| 5F10D7 | |
| Unconjugated | |
| PGRMC2 | |
| DG6, PGRMC2, PMBP | |
| Mouse | |
| Protein A | |
| RUO | |
| 10424, 70804 | |
| -20°C | |
| Liquid |
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