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Invitrogen™ Phospho-beta-2 Adrenergic Receptor (Ser346) Polyclonal Antibody
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Code produit. 16634335
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Quantité:
100 μL
Conditionnement:
100µL
Code produit. Quantité unitSize
16634335 100 μL 100µL
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Code produit. 16634335

Marque: Invitrogen™ PA5104767

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ADRB2 only when phosphorylated at Serine 346.

Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
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Specifica

Antigène Phospho-beta-2 Adrenergic Receptor (Ser346)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Expression Adrb2
Numéro d’ordre du gène P07550, P10608, P18762
Alias de gène Adrb2; Adrb-2; ADRB2R; ADRBR; Adrenergic beta 2- receptor surface; adrenergic receptor beta 2; adrenergic receptor, beta 2; adrenergic, beta-2, receptor, surface; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; AR beta2; B2AR; Badm; BAR; beta 2-AR; beta-2 adrenergic receptor; Beta-2 adrenoceptor; beta-2 adrenoreceptor; beta-2-adrenergic receptor; beta2-adrenergic receptor; beta2-Adrenoreceptor; BETA2AR; catecholamine receptor; Gpcr7; HGNC:286
Symboles de gène(s) Adrb2
Espèces hôtes Rabbit
Immunogène A synthesized peptide derived from human ADRB2(Accession P07550), corresponding to amino acid residues around phosphorylated Ser346.
Méthode de purification Sequential chromatography
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 11555, 154, 24176
Espèces cibles Human, Mouse, Rat
Contenu et stockage -20°C
Type de produit Antibody
Forme Liquid
Isotype IgG
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