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Invitrogen™ Phospho-NFkB p65 (Ser536) Monoclonal Antibody (T.849.2)
Rabbit Monoclonal Antibody
Marke: Invitrogen™ MA515160
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Beschreibung
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the p50 subunit or other related proteins.
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
Spezifikation
| Phospho-NFkB p65 (Ser536) | |
| Monoclonal | |
| 57 μg/mL | |
| 0.01M HEPES with 50% glycerol, 0.15M NaCl, 100 μg/mL BSA and <0.02% sodium azide, pH 7.5 | |
| Q04206, Q04207 | |
| RELA | |
| Synthetic phosphopeptide corresponding to residues surrounding pSer536 of human NFkB p65. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Monkey, Hamster, Pig | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry | |
| T.849.2 | |
| Unconjugated | |
| RELA | |
| avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 100135665, 100763542, 19697, 309165, 5970 | |
| -20°C | |
| Liquid |
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