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RADIL Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 20284-1-AP-150UL
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Description
Radil is a broadly expressed adapter protein that contains a RA-like domain, a PDZ domain and a DIL domain. Like RAPL and RIAM, Radil interacts preferentially with active GTP-bound Rap1, and overexpression of Radil enhances integrin-mediated adhesion. In addition, Radil knock down inhibits cell-substrate adhesion in HT1080, AD293, and NMuMG cells and results in migration defects in SW1353 and zebrafish neural crest cells. Radil regulates neutrophil adhesion by specifically enhancing beta2-integrin activation, as well as focal adhesion kinase (FAK) and paxillin phosphorylation.Spécification
| RADIL | |
| Polyclonal | |
| Unconjugated | |
| RADIL | |
| KIAA1849, RADIL | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 55698 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| 0.43 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q96JH8 | |
| RADIL | |
| RADIL Fusion Protein Ag13996 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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