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R&D Systems™ Recombinant Mouse IFN-alpha 2/IFNA2 Protein
Code nomenclature Nacres: NA.28
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Quantité:
10 μg
50 μg
Conditionnement:
10µg
50µg
Description
- IFN-alpha class members signal through a common cell surface receptor complex composed of IFN-alpha R2 and IFN-alpha R1 subunits
- The mature extracellular domain (ECD) of mouse IFN alpha -2 shares 60% and 83% aa sequence identity with human and rat, respectively
- Murine IFN-alpha 2 can eliminate cardiac viral load and protect cardiomyocytes from injury in animals infected with coxsackievirus B3 (CVB3)
- IFN alpha -2 derived mutants with reduced IFNR2 binding inhibited HIV replication and mutants with more IFNAR1 binding potentiated antiviral activity

Spécification
Spécification
Numéro d’adhésion | P01573 |
À utiliser avec (application) | Bioactivity |
Identification génétique (Entrez) | 3440 |
Poids moléculaire | 19.3 kDa |
Méthode de purification | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining |
Quantité | 10 μg |
Source | Human embryonic kidney cell, HEK293-derived mouse IFN-alpha 2/IFNA2 protein Cys24-Glu190 |
Conditions de stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after opening. 3 months, -20 to -70°C under sterile conditions after opening. |
Concentration en endotoxines | <0.10 EU per 1 μg of the protein by the LAL method |
Conjugué | Unconjugated |
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