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Invitrogen™ RGMB Polyclonal Antibody
Goat Polyclonal Antibody
Marque: Invitrogen™ PA547520
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Description
In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse RGM-B is observed and less than 1% cross-reactivity with recombinant human (rh) RGM-A and rhRGM-C is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.
Spécification
| RGMB | |
| Polyclonal | |
| Unconjugated | |
| RGMB | |
| 1110059F19Rik; DRAGON; DRG11-responsive axonal guidance and outgrowth of neurite; repulsive guidance molecule B; repulsive guidance molecule family member B; RGM domain family member B; RGM domain family, member B; RGMB | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 285704 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| Q6NW40 | |
| RGMB | |
| Mouse myeloma cell line NS0-derived recombinant human RGM-B isoform 1 Gly46-SerSer411. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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