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ACROBiosystems Rhesus macaque VEGF R2 / KDR Protein, His Tag
350.80€ - 2419.31€
Spécification
Poids moléculaire | 85.2 kDa |
---|---|
Source | Rhesus macaque VEGF R2, His Tag (VE2-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 764 (Accession # F7E313). |
Immunogène | Ala 20 - Glu 764 |
Conditions de stockage | -20°C |
Alias de gène | KDR,CD309,FLK1,VEGFR,VEGFR2 |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15867917
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ACROBiosystems
VE2-C52H3-100UG |
100 μg |
350.80€
100µg |
Expédition estimée: 24-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
15877917
|
ACROBiosystems
VE2-C52H3-1MG |
1 mg |
2419.31€
1mg |
Expédition estimée: 24-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Kinase insert domain receptor (KDR) is also known as CD309, FLK1, VEGFR, VEGFR2, and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF.The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 may be to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding (this appears to be particularly important during vasculogenesis in the embryo). In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 85.2 kDa. The protein migrates as 120-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
85.2 kDa | |
Ala 20 - Glu 764 | |
KDR,CD309,FLK1,VEGFR,VEGFR2 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>97% as determined by SDS-PAGE |
Rhesus macaque VEGF R2, His Tag (VE2-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 764 (Accession # F7E313). | |
-20°C | |
VEGF R2 | |
Rhesus Macaque | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |